Frenster JH, and Hovsepian JA, "Activator RNA Exchange during Interphase Chromatin Reprogramming".

Subjects of Study in Cell and Chromatin Reprogramming:

1. Active gene: A DNA sequence undergoing transcription to new RNA molecules.

2. Program: The pattern of active genes within a cell at a certain time and place.

3. Reprogramming: The molecular action that changes the program of a cell.

4. Telophase  Reprogramming: Post-mitotic reprogramming in late telophase.

5. Interphase Reprogramming: Reprogramming during the G0, S, or G1 phases.

6. Lineage: The program sequence that results in a differentiated cell.

7. Differentiated cell: A cell with a constricted program and a specialized function.

8. Stem Cell: A cell that self-replicates indefinitely.

9. Blastula: Determination phase of organ lineages.

10. Embryo: Early organ development.

11. Fetus: Intermediate organ development.

12. Infant: Late organ development.

13. Neoplasm: Re-expression of harmful embryonic DNA sequences.

14. Regeneration:  Re-expression of  useful embryonic DNA sequences.

15. Types of Reprogramming:

      a. Telophase Reprogramming: Endogenous activator RNA exchange.

      b. Interphase Reprogramming: Exogenous activator RNA exchange.

      c. DNA mutation: Covalent change in a DNA sequence.

      d. Epigenetic modification:  Covalent change without a DNA sequence change.

      e. Viral integration: Insertion or apposition of viral DNA sequence into DNA.

      f. Retrotransposon: Partial insertion or apposition of viral DNA or RNA.

      g.  Signal Reprogramming: Change in a program by change in signal intensity.

      h.  Nuclear Transplantation: Change in a program by change of the nucleus.

      i.   Oocyte Effect on Nucleus: Isolated nucleus incubation with oocyte.
 

Return to: "Activator RNA Exchange during Interphase Chromatin Reprogramming".

Summary of:  "Activator RNA Exchange during Interphase Chromatin Reprogramming".

Return to:  "RNA-Induced Chromatin Remodeling and DNA Melting during Selective Gene Transcription".


Further Topics in:  Euchromatin,  active DNA, and  RNA  ribo-regulators:

Links to Euchromatin Activator RNA Reviews:
Links to Euchromatin Activator RNA Research:
Links to Ultrastructural Probes of DNase I-Sensitive Sites:
Links to RNA as a Therapeutic Agent:
Links to Hodgkin Lymphoma Immuno-Pathology:
Links to Activated T-Lymphocyte Immunotherapy:
Links to Medical Systems Biology:

"Ultrastructural Probes of Active DNA Sites, and the RNA Activators of DNA".



Top of Page - Euchromatin Network - Current Research - Forums - Other Sites - Future Events -

For Further Information and Feedback:
E-mail: frenster@euchromatin.net



euchromatin: "the most active portion of the genome within the cell nucleus".