Weintraub H, Groudine M.

Ten percent digestion of isolated nuclei by pancreatic deoxyribonuclease I preferentially removes globin DNA sequences from nuclei obtained from chick red blood cells but not from nuclei obtained from fibroblasts, from brain, or from a population of red blood cell precursors. Moreover, the nontranscribed ovalbumin sequences in nuclei isolated from red blood cells and fibroblasts are retained after mild deoxyribonuclease I digestion. This suggests that active genes are preferentially digested by deoxyribonuclease I. In contrast, treatment of red cell nuclei with staphylococcal nuclease results in no preferential digestion of active globin genes. When the 11S monomers obtained after staphylococcal nuclease digestion of nuclei are then digested with deoxyribonuclease I, the active globin genes are again preferentially digested. The results indicate that active genes are probably associated with histones in a subunit conformation in which the associated DNA is particularly sensitive to digestion by deoxyribonuclease I.

PMID: 948749 [PubMed - indexed for MEDLINE] 

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27:  Groudine M, Weintraub H.
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28:  Smith RD, Yu J, Seale RL.
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31:  Emerson BM, Felsenfeld G.
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32:  Dimitriadis GJ, Tata JR.
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33:  Goodwin GH, Nicolas RH, Cockerill PN, Zavou S, Wright CA.
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34:  Itoh-Lindstrom Y, Leffak M.
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Nucleic Acids Res. 1994 Feb 11;22(3):498-505. Corrected and republished in:
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35:  Fisher EA, Felsenfeld G.
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36:  Lois R, Freeman L, Villeponteau B, Martinson HG.
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37:  Hutchison N, Weintraub H.
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38:  Hughes SH, Stubblefield E, Payvar F, Engel JD, Dodgson JB, Spector D,
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Proc Natl Acad Sci U S A. 1979 Mar;76(3):1348-52.
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39:  Postnikov IuV, Shik VV, Beliavskii AV, Brodolin KL, Khrapko KR, Nikol'skaia
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43:  Bloom KS, Anderson JN.
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45:  Brotherton TW, Reneker J, Ginder GD.
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46:  Weisbrod S, Groudine M, Weintraub H.
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47:  Palen TE, Cech TR.
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Nucleic Acids Res. 1983 Apr 11;11(7):2077-91.
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48:  Groudine M, Eisenman R, Weintraub H.
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49:  Groudine M, Weintraub H.
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50:  Kirov N, Tsanev R.
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51:  Balcarek JM, McMorris FA.
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52:  Itoh-Lindstrom Y, Leffak M.
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Nucleic Acids Res. 1994 Apr 11;22(7):498-505.
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53:  Spiker S, Murray MG, Thompson WF.
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54:  Vanderbilt JN, Bloom KS, Anderson JN.
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55:  Reeves R.
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57:  Dimitriadis GJ, Tata JR.
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61:  Bulger M, Schubeler D, Bender MA, Hamilton J, Farrell CM, Hardison RC,
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62:  Perry M, Chalkley R.
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63:  Levy-Wilson B, Kuehl L, Dixon GH.
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64:  Bloom KS, Anderson JN.
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65:  Vavra KJ, Pederson DS, Gorovsky MA.
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Nucleic Acids Res. 1981 Nov 11;9(21):5825-43.
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66:  Kuo MT, Iyer B, Schwarz RJ.
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Nucleic Acids Res. 1982 Aug 11;10(15):4565-79.
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67:  Motoyoshi K, Bank A, Rifkind RA, Marks PA.
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Biochim Biophys Acta. 1981 Mar 26;653(1):139-44.
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68:  Kohwi-Shigematsu T, Gelinas R, Weintraub H.
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Proc Natl Acad Sci U S A. 1983 Jul;80(14):4389-93.
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69:  Marcaud L, Reynaud CA, Therwath A, Scherrer K.
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Nucleic Acids Res. 1981 Apr 24;9(8):1841-51.
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70:  Razin SV, Mantieva VL, Georgiev GP.
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72:  Felber BK, Gerber-Huber S, Meier C, May FE, Westley B, Weber R, Ryffel GU.
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Nucleic Acids Res. 1981 Jun 11;9(11):2455-74.
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73:  Kuo MT.
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74:  Gerber-Huber S, Felber BK, Weber R, Ryffel GU.
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Nucleic Acids Res. 1981 Jun 11;9(11):2475-94.
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75:  Emerson BM, Nickol JM, Fong TC.
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76:  Myers FA, Evans DR, Clayton AL, Thorne AW, Crane-Robinson C.
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77:  Parlow MH, Haas AL, Lough J.
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78:  Cox MM, Lehman IR.
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79:  Rocha E, Davie JR, van Holde KE, Weintraub H.
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80:  Hebbes TR, Thorne AW, Crane-Robinson C.
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81:  Garel A, Axel R.
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82:  Haigh LS, Owens BB, Hellewell OS, Ingram VM.
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Proc Natl Acad Sci U S A. 1982 Sep;79(17):5332-6.
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83:  Emerson BM, Lewis CD, Felsenfeld G.
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84:  Lewis PN, Guillemette JG, Chan S.
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Eur J Biochem. 1988 Feb 15;172(1):135-45.
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85:  Groudine M, Peretz M, Weintraub H.
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Mol Cell Biol. 1981 Mar;1(3):281-8.
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86:  Samal B, Worcel A, Louis C, Schedl P.
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87:  Gottesfeld JM, Bloomer LS.
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88:  Kaye JS, Bellard M, Dretzen G, Bellard F, Chambon P.
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89:  Colquhoun WR, Holmes DS.
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90:  Dell'Orco RT, Whittle WL, Duncan MR, Robinson MJ.
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Mech Ageing Dev. 1983 Mar-Apr;21(3-4):273-82.
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91:  Weintraub H.
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92:  Komaiko W, Felsenfeld G.
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93:  Kootstra A.
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94:  Parslow TG, Granner DK.
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Nucleic Acids Res. 1983 Jul 25;11(14):4775-92.
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95:  Kirov N, Djondjurov L, Tsanev R.
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J Mol Biol. 1984 Dec 15;180(3):601-14.
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96:  Robinson SI, Nelkin BD, Vogelstein B.
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Nucleic Acids Res. 1980 Oct 24;8(20):4621-38.
PMID: 6255426 [PubMed - indexed for MEDLINE]

99:  Tsai SY, Roop DR, Stumph WE, Tsai MJ, O'Malley BW.
 Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are
not transcribed.
Biochemistry. 1980 Apr 29;19(9):1755-61.
PMID: 6246933 [PubMed - indexed for MEDLINE]

100:  Lachman HM, Mears JG.
 DNase I hypersensitivity in the gamma globin gene locus of K562 cells.
Nucleic Acids Res. 1983 Sep 10;11(17):6065-77.
PMID: 6310525 [PubMed - indexed for MEDLINE]

101:  Arrand JE, Murray AM.
 Benzpyrene groups bind preferentially to the DNA of active chromatin in human
lung cells.
Nucleic Acids Res. 1982 Mar 11;10(5):1547-55.
PMID: 6280150 [PubMed - indexed for MEDLINE]

102:  Evans RM, Baluda MA, Shoyab M.
 Differences between the integration of avian myeloblastosis virus DNA in
leukemic cells and of endogenous viral DNA in normal chicken cells.
Proc Natl Acad Sci U S A. 1974 Aug;71(8):3152-6. No abstract available.
PMID: 4369920 [PubMed - indexed for MEDLINE]

103:  Stalder J, Larsen A, Engel JD, Dolan M, Groudine M, Weintraub H.
 Tissue-specific DNA cleavages in the globin chromatin domain introduced by
DNAase I.
Cell. 1980 Jun;20(2):451-60. No abstract available.
PMID: 7388947 [PubMed - indexed for MEDLINE]

104:  Walmsley ME, Buckle RS, Allan J, Patient RK.
 A chicken red cell inhibitor of transcription associated with the terminally
differentiated state.
J Cell Biol. 1991 Jul;114(1):9-19.
PMID: 2050744 [PubMed - indexed for MEDLINE]

105:  Zasloff M, Camerini-Otero RD.
 Limited DNase I nicking as a probe of gene conformation.
Proc Natl Acad Sci U S A. 1980 Apr;77(4):1907-11.
PMID: 6929527 [PubMed - indexed for MEDLINE]

106:  Smith RD, Yu J, Annunziato A, Seale RL.
 beta-Globin gene family in murine erythroleukemia cells resides within two
chromatin domains differing in higher order structure.
Biochemistry. 1984 Jun 19;23(13):2970-6.
PMID: 6235849 [PubMed - indexed for MEDLINE]

107:  Kimura T, Mills FC, Allan J, Gould H.
 Selective unfolding of erythroid chromatin in the region of the active
beta-globin gene.
Nature. 1983 Dec 15-21;306(5944):709-12.
PMID: 6656872 [PubMed - indexed for MEDLINE]

108:  Sun YL, Xu YZ, Bellard M, Chambon P.
 Digestion of the chicken beta-globin gene chromatin with micrococcal nuclease
reveals the presence of an altered nucleosomal array characterized by an
atypical ladder of DNA fragments.
EMBO J. 1986 Feb;5(2):293-300.
PMID: 3011400 [PubMed - indexed for MEDLINE]

109:  Giri CP, Gorovsky MA.
 DNase I sensitivity of ribosomal genes in isolated nucleosome core particles.
Nucleic Acids Res. 1980 Jan 11;8(1):197-214.
PMID: 6766552 [PubMed - indexed for MEDLINE]

110:  Kuo MT.
 Distribution of tightly bound proteins in the chicken ovalbumin gene region.
Biochemistry. 1982 Jan 19;21(2):321-6.
PMID: 6896157 [PubMed - indexed for MEDLINE]

111:  Villeponteau B, Martinson HG.
 Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of
beta-globin gene chromatin in vivo.
Mol Cell Biol. 1987 May;7(5):1917-24.
PMID: 2439900 [PubMed - indexed for MEDLINE]

112:  Weintraub H, Flint SJ, Leffak IM, Groudine M, Grainger RM.
 The generation and propagation of variegated chromosome structures.
Cold Spring Harb Symp Quant Biol. 1978;42 Pt 1:401-7. No abstract available.
PMID: 277354 [PubMed - indexed for MEDLINE]

113:  Gentry GA, Evans S, Campbell DE.
 Herpesvirus-induced availability of host DNA to exogenous endonuclease.
Acta Virol. 1975 Sep;19(5):401-5.
PMID: 241244 [PubMed - indexed for MEDLINE]

114:  Kroeker WD, Kowalski D.
 Gene-sized pieces produced by digestion of linear duplex DNA with mung bean
nuclease.
Biochemistry. 1978 Aug 8;17(16):3236-43. No abstract available.
PMID: 687580 [PubMed - indexed for MEDLINE]

115:  Walbot V.
 Stability of mercurated DNA during reassociation and S1 nuclease digestion
experiments.
Anal Biochem. 1978 Oct 1;90(1):90-7. No abstract available.
PMID: 727490 [PubMed - indexed for MEDLINE]
 

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